Cigarettes & Wine

Conjecture

Cigarettes and Wine are 2 big LEGAL SUBSTANCES that can be extremely problematic from a health perspective.

But isolating NICOTINE and RESVERATROL from Wine seem to have benefits.

NICOTINE is already being used to help people get off the COMBUSTIBLE USE OF NICOTINE.

At least some Neuro-Diverse people --- smoke cigarettes to calm themselves down.

I have mentioned before that I think it very interesting that part of our MENTAL HEALTH CRISIS is coinciding with a reduction of CIGARETTE SMOKING ---

• People aren't dying as young from preventable illnesses --- but they do seem to be MORE ON EDGE and having a harder time with Mental Health.

Correlation is NOT CAUSALITY -- BUT it should prompt us to INVESTIGATE FURTHER.

I think NICOTINE may help some Neuro-Diverse people calm down --- but even if that is true we're still talking about IDIOSYNCRATIC BIOLOGIES in which in an IDEAL WORLD that NICOTINE DOSE is TITRATED based on Evidence-Based Research and able to be SELF-MONITORED based on a RANGE.

• NOT UNLIKE BLOOD PRESSURE,
• & NICOTINE can effect BLOOD PRESSURE among other things.

I think there are a lot of reasons why we would want that at the LOWEST POSSIBLE DOSE ---

• IF it proved helpful and the SIDE EFFECTS didn't outweigh the BENEFITS.

RESVERATROL is being celebrated for its ANTI-AGING properties ---

• That is important to everyone ---
• It should be especially important to NEURO-DIVERSE people who may have come pre-packaged with a large dose of SYSTEMIC DEVELOPMENTAL INFLAMMATION.

Smoking during pregnancy with a genetic risk triples the risk the baby will have ADHD

Past research has suggested that both genes and prenatal insults -- such as exposure to alcohol and nicotine -- can increase the risk of attention-deficit/hyperactivity disorder (ADHD).

But the identified increases in risk have been very modest.

Now, scientists has found that when those factors are studied together, risk of a severe type of ADHD greatly increases. .   .  .

"But when we looked at the effect of maternal smoking in children with one of our candidate genes, we saw a three-fold increase in risk, and in children with both genes whose mothers smoked during pregnancy, we saw a nine-fold increase," says senior investigator Richard D. Todd, M.D., Ph.D., the Blanche F. Ittleson Professor and director of the Division of Child Psychiatry at Washington University.

"Our findings begin to offer an explanation for the modest effects we've seen when looking at genes or environmental variables one at a time. It appears it's really the interaction of genes and environmental factors that predisposes a child to problems with ADHD."

I think the issue of Developmental Systemic Inflammation has been very common throughout HUMAN HISTORY.

Smoking by women in the 20th Century increasing what was already there.

FOR HOW MANY GENERATIONS WILL THOSE EFFECTS BE SEEN?