Blog Archives

Immunologic Dysfunction and Psychiatric Disorders

4/25/2022

Prenatal Exposure Proinflammatory Cytokines Risk ...https://advances.massgeneral.org › neuro › journal

Nov 22, 2021 -- Jill M. Goldstein, PhD, of the Department of Psychiatry, ... Cytokines May Increase Risk of Psychiatric Disorders by Sex 45 years later in ...
Glial Cells and Pro-inflammatory Cytokines as Shared ...https://oxfordmedicine.com › view › med › med-97801...

Many cytokines have been implicated in both pain and psychiatric disorders, including interleukin-1β‎ (IL-1β‎), tumor necrosis factor-α‎, and IL-6. More ...
Cytokines as Biomarkers in Psychiatric Disorders - SpringerLink https://link.springer.com › chapter

by O Khalfallah · 2021 -- Previous studies have shown that most severe mental disorders are associated with altered blood levels of cytokines, a group of small soluble ...
Inflammation Subtypes and Translating Inflammation-Related ...https://journals.lww.com › hrpjournal › Fulltext › Inflam...

Separately, disease-risk genetic studies of psychotic disorders have identified ... in many peripheral cytokines between psychiatric patients and controls.

by B Dawidowski · 2021 Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling body of evidence implicates immunologic dysfunction as the key ...

The Role of Cytokines in the Pathogenesis of Schizophrenia

by N Groven · 2018 Association between cytokines and psychiatric symptoms in chronic fatigue syndrome and healthy controls

SUSTAINABILITY ---Human Limits and Hyper-Connected, Hyper-Plastic Brains

4/12/2022

When we think about SUSTAINABILITY -- we tend to think about CLIMATE --- BUT we need to start thinking about HUMAN BEINGS.

In recent years, we have become quite enamored with the idea of BRAIN PLASTICITY.
- It is fascinating and there probably is A LOT that will be gained from better understanding BRAIN PLASTICITY.

One of the first places we might want to start is Neuro-Developmental Differences / Disorders and Psychiatric Disorders.

We might think --- "Oh, people with these differences and/or disorders --- have LITTLE BRAIN PLASTICITY."

BUT THAT IS NOT THE CASE.

In fact, the OPPOSITE is often the case.

People with Neuro-Developmental Differences / Disorders and Psychiatric Disorders tend to have "HYPER-CONNECTED BRAINS" and greater PLASTICITY.

Having an ACCURATE UNDERSTANDING of BRAIN PLASTICITY is going to be IMPORTANT for the "TREATMENT" of Neuro-Developmental Differences / Disorders and Psychiatric Disorders.

Understanding BOTH COMMON & IDIOSYNCRATIC DIFFERENCES among NEURO-DIVERSE PEOPLE---- especially when it comes to:

EXECUTIVE FUNCTIONING
SENSORY PROCESSING and
EMOTIONAL OVERWHELM

and TRANSLATING a NEURO-TYPICAL APPROACH to someone who is:

NEURO-DIVERSE
Likely already has a HYPER-CONNECTED BRAIN
and can often be CLOSE TO THEIR LIMITS ---

THIS IS CRITICAL.

I'm not saying that we can't use BRAIN PLASTICITY for the benefit of people with Neuro-Developmental Differences/ Disorders and Psychiatric Disorders:

BUT we need to respect their/my "BOUNDARIES"
We need to include them/me even more as "PARTNERS" in "TREATMENT," Family and Community Life.

This is NOT just for Mental Health Professionals --- This is for all of us -- Individuals, Families, Communities and Institutions.

Neuro-Diversity has so much to offer the world --- Neuro-Diverse people are primarily who we study in school --- BUT if we want a SOCIETY that can adequately handle the SCALE of Neuro-Diversity in the Population ---We need to address Neuro-Diversity MORE CONSCIOUSLY ---- There are some BIG STRENGTHS, there are also some BIG LIMITS.

Future Learn

The Limits of Neuroplasticity | Discover Magazine https://www.discovermagazine.com › health › the-limits... Nov 13, 2010 — If the brain were infinitely plastic, brain damage would be no big deal. You'd get over it pretty quickly, so long as some of your brain was ...

Neuroplasticity: How Experience Changes the Brain https://www.verywellmind.com › what-is-brain-plasticit...

Feb 18, 2022 — Brain Plasticity Also Has Limitations ... It is important to note, however, that the brain is not infinitely malleable. Certain areas of the brain ...

New Scientist ------ Maxxed Out: Testing Humans to Destruction

Translational Medicine Friday

We're riffing off NPR's Science Friday to create Translational Medicine Friday.

We'll be collecting Research Article recommendations for Clinicians with regard to Cognitive Disability.

There is much in the RESEARCH JOURNALS and we'll just be SKIMMING THE SURFACE.

The POINT is to INCREASE FUNDING for TRANSLATIONAL RESEARCH at the Federal Level for the National Institutes of Health, the Centers for Disease Control, the Nation's Research & Teaching Hospitals and possible collaborations with Medicare and Medicaid providers.

Translational Medicine Friday

Immunologic Dysfunction and Psychiatric Disorders

SUSTAINABILITY ---​Human Limits and Hyper-Connected, Hyper-Plastic Brains

Translational Medicine Friday

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SUSTAINABILITY ---Human Limits and Hyper-Connected, Hyper-Plastic Brains